Gene library · Complex disease risk
Coronary artery disease risk (9p21)
rs10757278 · gene 9p21 (CDKN2B-AS1) · category Complex disease risk · Quanome Plus
Your DNA file reports your genotype at rs10757278 — a marker in the 9p21 (CDKN2B-AS1) gene that studies link to coronary artery disease risk (9p21). Here's what each genotype is associated with:
| Genotype | What it's associated with |
|---|---|
| AA | Lower-risk genotype at the 9p21 locus, a well-replicated coronary-artery-disease marker — average background risk here. |
| AG | One risk (G) allele — modestly higher coronary-artery-disease risk. Strongly modifiable by blood pressure, lipids, smoking and activity. Not a diagnosis. |
| GG | Two risk (G) alleles — higher coronary-artery-disease risk at this marker. Largely modifiable by cardiovascular risk factors; informational, not a diagnosis. |
Want to read rs10757278 in your own data? The free DNA explorer checks it in your browser — nothing is uploaded. Or get the full picture in Quanome, which reads your whole genome on-device alongside your labs and Apple Health.
