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Gene library · Complex disease risk

Type 2 diabetes risk (TCF7L2)

rs7903146 · gene TCF7L2 · category Complex disease risk · Quanome Plus

Your DNA file reports your genotype at rs7903146 — a marker in the TCF7L2 gene that studies link to type 2 diabetes risk (tcf7l2). Here's what each genotype is associated with:

GenotypeWhat it's associated with
CCLower-risk genotype at TCF7L2, the strongest common type-2-diabetes marker — average background risk here.
CTOne risk (T) allele — modestly higher type-2-diabetes risk than average. Strongly modifiable by weight, diet and activity. Not a diagnosis.
TTTwo risk (T) alleles — higher type-2-diabetes risk at this marker (roughly double the C/C background). Largely modifiable by lifestyle; informational, not a diagnosis.

Educational only — not medical or diagnostic advice. A single marker is one of many factors; strand orientation varies between files. Always consult a qualified clinician about your health.

Want to read rs7903146 in your own data? The free DNA explorer checks it in your browser — nothing is uploaded. Or get the full picture in Quanome, which reads your whole genome on-device alongside your labs and Apple Health.

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