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Gene library · Pharmacogenomics

Statin muscle-symptom risk

rs4149056 · gene SLCO1B1 · category Pharmacogenomics · Quanome Plus

Your DNA file reports your genotype at rs4149056 — a marker in the SLCO1B1 gene that studies link to statin muscle-symptom risk. Here's what each genotype is associated with:

GenotypeWhat it's associated with
TTNormal SLCO1B1 transport — typical statin handling.
CTOne reduced-function copy — somewhat higher chance of statin-related muscle symptoms. Informational.
CCReduced transport — higher chance of statin muscle symptoms (esp. simvastatin). Informational; discuss with a professional.

Educational only — not medical or diagnostic advice. A single marker is one of many factors; strand orientation varies between files. Always consult a qualified clinician about your health.

Want to read rs4149056 in your own data? The free DNA explorer checks it in your browser — nothing is uploaded. Or get the full picture in Quanome, which reads your whole genome on-device alongside your labs and Apple Health.

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