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Gene library · Health markers

Alpha-1 antitrypsin — Pi*Z

rs28929474 · gene SERPINA1 · category Health markers · Free in the Quanome app

Your DNA file reports your genotype at rs28929474 — a marker in the SERPINA1 gene that studies link to alpha-1 antitrypsin — pi*z. Here's what each genotype is associated with:

GenotypeWhat it's associated with
CCNo Z allele.
CGOne Z allele (MZ) — carrier; usually a mild effect.
GGTwo Z alleles (ZZ) — linked to alpha-1 antitrypsin deficiency. Discuss with a clinician.

Educational only — not medical or diagnostic advice. A single marker is one of many factors; strand orientation varies between files. Always consult a qualified clinician about your health.

Want to read rs28929474 in your own data? The free DNA explorer checks it in your browser — nothing is uploaded. Or get the full picture in Quanome, which reads your whole genome on-device alongside your labs and Apple Health.

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