Folate processing (A1298C)

rs1801131 · gene MTHFR · category Nutrition · Free in the Quanome app

Your DNA file reports your genotype at rs1801131 — a marker in the MTHFR gene that studies link to folate processing (a1298c). Here's what each genotype is associated with:

Genotype	What it's associated with
AA	Typical MTHFR (A1298C) activity.
AC	One A1298C variant — slightly reduced activity.
CC	Two A1298C variants — reduced activity (compounding with C677T if present).

Educational only — not medical or diagnostic advice. A single marker is one of many factors; strand orientation varies between files. Always consult a qualified clinician about your health.

Want to read rs1801131 in your own data? The free DNA explorer checks it in your browser — nothing is uploaded. Or get the full picture in Quanome, which reads your whole genome on-device alongside your labs and Apple Health.

Folate processing (A1298C)

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