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Gene library · Health markers

Celiac disease genetic risk (HLA-DQ2.5 tag)

rs2187668 · gene HLA-DQA1 · category Health markers · Free in the Quanome app

Your DNA file reports your genotype at rs2187668 — a marker in the HLA-DQA1 gene that studies link to celiac disease genetic risk (hla-dq2.5 tag). Here's what each genotype is associated with:

GenotypeWhat it's associated with
CCHLA-DQ2.5 tag not detected — lower genetic predisposition (not a rule-out).
CTCarries one copy of the HLA-DQ2.5 tag — higher genetic predisposition to celiac disease. Most carriers never develop it.
TTCarries two copies of the HLA-DQ2.5 tag — higher genetic predisposition to celiac disease. Most carriers never develop it.

Educational only — not medical or diagnostic advice. A single marker is one of many factors; strand orientation varies between files. Always consult a qualified clinician about your health.

Want to read rs2187668 in your own data? The free DNA explorer checks it in your browser — nothing is uploaded. Or get the full picture in Quanome, which reads your whole genome on-device alongside your labs and Apple Health.

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