Quanome.

Gene library · Pharmacogenomics

CYP2C19 metabolism (*3)

rs4986893 · gene CYP2C19 · category Pharmacogenomics · Quanome Plus

Your DNA file reports your genotype at rs4986893 — a marker in the CYP2C19 gene that studies link to cyp2c19 metabolism (*3). Here's what each genotype is associated with:

GenotypeWhat it's associated with
AATwo *3 copies (poor metabolizer) — drugs like clopidogrel, some PPIs and antidepressants may work differently. Informational only; never change medication without your doctor.
AGOne reduced-function *3 copy — intermediate CYP2C19 metabolism; some of these drugs may be processed more slowly. Informational; discuss with a professional.
GGNormal CYP2C19 function at this marker — typical metabolism of clopidogrel, some PPIs and antidepressants. Read alongside the *2 and *17 markers.

Educational only — not medical or diagnostic advice. A single marker is one of many factors; strand orientation varies between files. Always consult a qualified clinician about your health.

Want to read rs4986893 in your own data? The free DNA explorer checks it in your browser — nothing is uploaded. Or get the full picture in Quanome, which reads your whole genome on-device alongside your labs and Apple Health.

See all your genes in one place

Quanome reads your full DNA file on your device — traits, nutrition, fitness, and more — alongside your labs and Apple Health. Join the waitlist for early access.