Gene library · Pharmacogenomics
CYP2C19 metabolism (*3)
rs4986893 · gene CYP2C19 · category Pharmacogenomics · Quanome Plus
Your DNA file reports your genotype at rs4986893 — a marker in the CYP2C19 gene that studies link to cyp2c19 metabolism (*3). Here's what each genotype is associated with:
| Genotype | What it's associated with |
|---|---|
| AA | Two *3 copies (poor metabolizer) — drugs like clopidogrel, some PPIs and antidepressants may work differently. Informational only; never change medication without your doctor. |
| AG | One reduced-function *3 copy — intermediate CYP2C19 metabolism; some of these drugs may be processed more slowly. Informational; discuss with a professional. |
| GG | Normal CYP2C19 function at this marker — typical metabolism of clopidogrel, some PPIs and antidepressants. Read alongside the *2 and *17 markers. |
Want to read rs4986893 in your own data? The free DNA explorer checks it in your browser — nothing is uploaded. Or get the full picture in Quanome, which reads your whole genome on-device alongside your labs and Apple Health.
