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Gene library · Trait

Dopamine clearance (Val158Met)

rs4680 · gene COMT · category Trait · Free in the Quanome app

Your DNA file reports your genotype at rs4680 — a marker in the COMT gene that studies link to dopamine clearance (val158met). Here's what each genotype is associated with:

GenotypeWhat it's associated with
GGVal/Val — faster dopamine clearance; the 'warrior' type in some studies (weak effect).
AGVal/Met — intermediate.
AAMet/Met — slower dopamine clearance; the 'worrier' type; possibly more stress-sensitive (weak effect).

Educational only — not medical or diagnostic advice. A single marker is one of many factors; strand orientation varies between files. Always consult a qualified clinician about your health.

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