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Gene library · Complex disease risk

Macular degeneration risk (ARMS2)

rs10490924 · gene ARMS2/HTRA1 · category Complex disease risk · Quanome Plus

Your DNA file reports your genotype at rs10490924 — a marker in the ARMS2/HTRA1 gene that studies link to macular degeneration risk (arms2). Here's what each genotype is associated with:

GenotypeWhat it's associated with
GGLower-risk genotype at ARMS2/HTRA1 — average age-related-macular-degeneration risk here.
GTOne risk (T, Ser69) allele — moderately higher macular-degeneration risk. Informational.
TTTwo risk (T) alleles — higher age-related-macular-degeneration risk at this marker. Not smoking and eye-healthy nutrition help; informational, not a diagnosis.

Educational only — not medical or diagnostic advice. A single marker is one of many factors; strand orientation varies between files. Always consult a qualified clinician about your health.

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