Gene library · Pharmacogenomics
ABCG2 transporter (Q141K)
rs2231142 · gene ABCG2 · category Pharmacogenomics · Quanome Plus
Your DNA file reports your genotype at rs2231142 — a marker in the ABCG2 gene that studies link to abcg2 transporter (q141k). Here's what each genotype is associated with:
| Genotype | What it's associated with |
|---|---|
| GG | Normal ABCG2 transporter function — typical handling of rosuvastatin and allopurinol. |
| GT | One reduced-function (141K) allele — somewhat higher rosuvastatin exposure; intermediate. Informational. |
| TT | Two reduced-function (141K) alleles — higher rosuvastatin levels (lower doses may suffice) and often better allopurinol response. Informational; discuss with a professional. |
Want to read rs2231142 in your own data? The free DNA explorer checks it in your browser — nothing is uploaded. Or get the full picture in Quanome, which reads your whole genome on-device alongside your labs and Apple Health.
